Global Health Economics and Outcomes Research

We help harness evidence to provide patients with access to innovative medical interventions. We design and execute research to understand product value and the patient-centered impact of your treatments and medical devices. We leverage deep expertise, robust methodologies and strong analytics to achieve your goals. We then help you communicate this value to support payer, provider and patient access.


Challenges we solve

We generate, synthesize and present evidence that is tailored to the unique and evolving needs of different stakeholders, preparing health systems to recognize and reimburse the value of medical interventions.

Evidence synthesis

We build a robust foundation for evidence-based decision-making by leveraging advanced evidence synthesis methodologies. Our goal is to identify unmet therapeutic value, disease burden, epidemiology, comparative effectiveness and budgetary impact.

Health economic modeling

Our experts help determine the economic impact of a therapeutic intervention to deliver strategic vision and drive decision-making, pipeline strategy and product value narratives for internal and external audiences.

Value and evidence communications

We leverage deep clinical and economic insights to develop and communicate a clear evidence generation framework for therapeutic value that is tailored to market nuances, the needs of key stakeholders and unmet patient needs. 


ZS’s approach

We passionately believe that our work translating evidence to value should have real-world impact. Our diverse experts and extended advisors work as one integrated team to help define, discover and deliver value in the most impactful way.

Quantitative evidence synthesis

Comparative data often cannot be generated in clinical trials. We conduct rigorous statistical analyses of multisource data to evaluate its heterogeneity and uncertainty, facilitating an understanding of a product’s relative value.

Context to demonstrate value

Value can only be demonstrated if the context is correctly set. Our team builds this context by understanding and quantifying the clinical, human and economic impact of diseases, in a format specifically tailored to the needs of the target audience.

Value codified through modeling

Theoretical value needs to be codified. We achieve this when we bring insight, evidence and technical excellence together to create a suite of health economic models, including all forms of budget impact and cost-effectiveness models. Our digital economic models feature added UX, visual and emotional impact.

Digital global value dossiers

Our communication work incorporates the art of storytelling, deep understanding of audiences and expert medical writing to ensure that value resonates. Our digital global value dossiers include advanced UX design features suitable for the digital era. 

Qualitative evidence synthesis

A complete multiperspective evidence story is necessary to drive decision-making. We use sophisticated evidence synthesis methods and stakeholder engagement frameworks to qualitatively synthesize evidence and drive system-level change.

Audience-focused communications

We devise publication and execution strategies and create tailored communications designed to express your product’s value in ways that resonate with your key audiences.